We were totally surprised when the sufferers had a panic attack, says Wemmie, a faculty member in the Iowa Neuroscience Graduate Program also. By contrast, only three of 12 healthy participants panicked-a rate similar to adults with no history of anxiety attacks. Notably, none of the three sufferers with amygdala damage has a history of panic attacks. The bigger rate of carbon dioxide-induced panic in the patients shows that an intact amygdala might normally inhibit panic. Interestingly, the amygdala-damaged patients had no fear resulting in the test up, unlike the healthy participants, many who began sweating and whose heart prices rose before inhaling the carbon dioxide just. That, of course, was consistent with the idea that the amygdala detects danger in the external environment and physiologically prepares the organism to confront the threat.The principal endpoint was a composite of all-trigger mortality or main stroke rate at 12 months; the Kaplan-Meier motivated event rate was compared with a pre-specified objective efficiency goal . Of the 487 patients enrolled in the study, 471 had an attempted implantation and were designated as the primary as treated analysis human population. Patients were elderly , and were severely symptomatic . The Culture for Thoracic Medical procedures Predicted Threat of Mortality was 10.3 % – 5.6 % and was 15 % in 17 >.6 % of patients. At 12 months, the composite rate of death or main stroke was 25.5 %, below the 95 % confidence interval of the performance goal significantly, that was set at 43 %.